Description

Aminooxy-Peg7-Methane CAS NO 1370698-27-3 is a heterobifunctional polyethylene glycol (PEG) linker featuring a reactive aminooxy group and a methoxy terminus. This compound is engineered for site-specific bioconjugation, enabling the stable oxime bond formation with ketone or aldehyde groups under mild, aqueous conditions. It is an essential tool for researchers and manufacturers in the fields of biopharmaceutical development, advanced diagnostics, and materials science, where precise and stable modification of biomolecules is required.

Application

• Bioconjugation Reagent: For the site-specific labeling of antibodies, proteins, peptides, and oligonucleotides containing ketone or aldehyde functionalities.
• ADC (Antibody-Drug Conjugate) Linker: Enables the controlled attachment of cytotoxic payloads to monoclonal antibodies via oxime chemistry for targeted cancer therapies.
• PEGylation Agent: Used to modify therapeutic proteins and peptides to enhance solubility, reduce immunogenicity, and prolong circulation half-life in vivo.
• Surface Functionalization: For creating functionalized surfaces on biosensors, microarrays, and nanoparticles for specific biomolecule capture.
• Crosslinking Reagent: In the development of hydrogels, biomaterials, and polymer networks requiring specific, stable covalent linkages.
• Diagnostic Probe Synthesis: For conjugating fluorophores, enzymes, or other reporter molecules to targeting moieties in assay development.

Basic Information

Product Name	Aminooxy-Peg7-Methane
CAS No.	1370698-27-3
Molecular Formula	C17H35NO9
Molecular Weight	397.46 g/mol
Synonyms	Aminooxy-PEG7-methoxy; Aminooxy-PEG7-OMe; O-(2-Aminooxyethyl)heptaethylene glycol methyl ether; Methoxy-PEG7-aminooxy; Heptaethylene glycol monomethyl ether aminooxy derivative; Aminooxy functionalized PEG7 methyl ether; Aminooxy-PEG7-CH3; Aminooxy-PEG7-methane
EINECS	Contact for details

Quality Control

Our Aminooxy-Peg7-Methane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance for critical research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and functional group integrity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) in a dry, cool environment. Due to its hygroscopic and easily oxidized nature, allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or oil
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Functional Group Assay	≥ 90% (Aminooxy)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.