Description

Benzenamine, 2-[(4R,5R)-4,5-Dihydro-4,5-Diphenyl-2-Oxazolyl]-n-[2-[(4R,5R)-4,5-Dihydro-4,5-Diphenyl-2-Oxazolyl]Phenyl]- is a sophisticated chiral bis(oxazoline) ligand derivative, a key building block in advanced asymmetric synthesis. This compound matters for its role as a highly selective catalyst precursor or chiral auxiliary, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel synthetic routes.

Application

• Asymmetric Catalysis: As a chiral ligand for transition metal-catalyzed reactions including Diels-Alder, cyclopropanation, and aldol additions.
• Pharmaceutical Intermediate Synthesis: For the enantioselective construction of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Research: In the development of chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: As a precursor for chiral polymers or metal-organic frameworks (MOFs) with specific optical properties.
• Academic & Industrial R&D: A critical tool for methodological development in organic and organometallic chemistry laboratories.
• Fine Chemical Production: For the commercial-scale manufacture of high-value, enantiopure flavor and fragrance compounds.

Basic Information

Product Name	Benzenamine, 2-[(4R,5R)-4,5-Dihydro-4,5-Diphenyl-2-Oxazolyl]-n-[2-[(4R,5R)-4,5-Dihydro-4,5-Diphenyl-2-Oxazolyl]Phenyl]-
CAS No.	1370549-65-7
Molecular Formula	C42H32N4O2
Molecular Weight	624.74 g/mol
Synonyms	N,N'-Bis[2-((4R,5R)-4,5-Dihydro-4,5-diphenyl-2-oxazolyl)phenyl]-1,2-benzenediamine; Bis(oxazoline) Diamine Derivative; Chiral C2-Symmetric Bisoxazoline Ligand; (R,R)-Bis(PhBOX) Aniline Derivative; 1,2-Phenylenediamine, N,N'-bis[2-[(4R,5R)-4,5-dihydro-4,5-diphenyl-2-oxazolyl]]-; Asymmetric Catalyst Ligand 1370549-65-7
EINECS	Contact for details

Quality Control

Our production of this advanced chiral chemical adheres to strict quality protocols to ensure batch-to-batch consistency and enantiomeric purity critical for research and process development. Quality is verified through comprehensive analytical techniques including HPLC, chiral HPLC, and 1H/13C NMR. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, enantiomeric excess (ee), and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.