Description

Ethyl 3-(4-Bromophenyl)Oxetane-3-Carboxylate CAS NO 1370035-61-2 is a high-value, synthetically versatile oxetane derivative used as a key building block in advanced organic synthesis. This compound is critical for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs) due to its unique strained ring system and functional handles. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Medicinal Chemistry Scaffold: Used as a core scaffold or a conformational constraint element to modulate the biological activity, metabolic stability, and physicochemical properties of new chemical entities.
• Agrochemical Research: Employed in the development of novel herbicides, fungicides, and insecticides, leveraging the oxetane moiety to enhance efficacy and environmental profile.
• Material Science Monomer: Investigated as a monomer for creating polymers with unique thermal and mechanical properties, useful in coatings and advanced materials.
• Chemical Biology Probe Synthesis: Utilized to build molecular probes for studying enzyme function and biological pathways in academic and industrial research settings.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and pilot-scale production of target molecules under current Good Manufacturing Practice (cGMP) guidelines where required.

Basic Information

Product Name	Ethyl 3-(4-Bromophenyl)Oxetane-3-Carboxylate
CAS No.	1370035-61-2
Molecular Formula	C12H13BrO3
Molecular Weight	285.14 g/mol
Synonyms	Ethyl 3-(4-bromophenyl)oxetane-3-carboxylate; 3-Oxetanecarboxylic acid, 3-(4-bromophenyl)-, ethyl ester; Ethyl 3-(p-bromophenyl)oxetane-3-carboxylate; 4-Bromo-α-(2-oxetanyl)benzenepropanoic acid ethyl ester; Oxetane-3-carboxylic acid, 3-(4-bromophenyl)-, ethyl ester; 1370035-61-2; AI3-52335
EINECS	Contact for details

Quality Control

Our Ethyl 3-(4-Bromophenyl)Oxetane-3-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as identity, purity, and impurity profiles. Our quality systems are designed to support both non-GMP and cGMP requirements for early-phase and commercial pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.