Description

5-Bromo-2-Ethoxy-1-Fluoro-3-(Trifluoromethyl)Benzene is a high-purity, multi-functional halogenated benzene derivative designed for advanced chemical synthesis. This compound is a critical building block in pharmaceutical and agrochemical research, valued for its unique combination of bromo, fluoro, and trifluoromethyl substituents which enable precise molecular modifications. It is primarily sought by R&D chemists and process development scientists in the life sciences and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Fluorine Chemistry Research: An important compound for studying structure-activity relationships (SAR) and the effects of fluorination on molecular properties in medicinal and agrochemistry.

Basic Information

Product Name	5-Bromo-2-Ethoxy-1-Fluoro-3-(Trifluoromethyl)Benzene
CAS No.	1370025-61-8
Molecular Formula	C9H7BrF4O
Molecular Weight	287.05 g/mol
Synonyms	1-Bromo-4-ethoxy-2-fluoro-5-(trifluoromethyl)benzene; 2-Ethoxy-5-bromo-1-fluoro-3-(trifluoromethyl)benzene; 5-Bromo-2-ethoxy-1-fluoro-3-(trifluoromethyl)benzene; Benzene, 5-bromo-2-ethoxy-1-fluoro-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Ethoxy-1-Fluoro-3-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.