Description

2-Bromo-6-Fluorothioanisole is a high-purity, halogenated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular structure, which serves as a versatile intermediate for constructing complex molecules in regulated industries. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the bromo and fluoro substituents contribute to biological activity.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology: Employed as a building block for synthesizing molecular probes and ligands for biochemical assays and diagnostic applications.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination.
• Functional Group Transformation: Used in multi-step synthetic routes to introduce sulfur-containing motifs or to further functionalize the aromatic core.

Basic Information

Product Name	2-Bromo-6-Fluorothioanisole
CAS No.	1370025-53-8
Molecular Formula	C7H6BrFS
Molecular Weight	221.09 g/mol
Synonyms	1-Bromo-2-fluoro-3-(methylthio)benzene; 2-Bromo-6-fluoro-1-(methylthio)benzene; 3-Bromo-2-fluorophenyl methyl sulfide; Methyl 3-bromo-2-fluorophenyl sulfide; 2-Fluoro-6-bromothioanisole; 1-Fluoro-2-bromo-3-(methylthio)benzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Fluorothioanisole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.