Description

3-Amino-2-Fluorobenzamide is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both an amino and a fluorinated amide group, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to develop fluorescent tags and molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-Amino-2-Fluorobenzamide
CAS No.	1369948-83-3
Molecular Formula	C7H7FN2O
Molecular Weight	154.14 g/mol
Synonyms	2-Fluoro-3-aminobenzamide; 3-Amino-2-fluorobenzoic acid amide; Benzoic acid, 3-amino-2-fluoro-, amide; 2-Fluoro-3-aminobenzamide; 3-Amino-2-fluorobenzamide; 1369948-83-3; AI3-52362; AKOS040759623; ZINC000068049772; SCHEMBL21824027; MFCD28124260
EINECS	Contact for details

Quality Control

Our 3-Amino-2-Fluorobenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.