Description

2-Chloro-1-Iodo-3-(Trifluoromethyl)Benzene is a high-value halogenated aromatic building block, distinguished by its unique combination of chlorine, iodine, and trifluoromethyl substituents. This compound is critical for facilitating advanced cross-coupling reactions and introducing fluorinated motifs into target molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki, Stille, and Negishi cross-coupling reactions for constructing complex biaryl structures in drug discovery and development.
• Agrochemical Synthesis: Used to incorporate the trifluoromethyl group into novel herbicides, fungicides, and insecticides, enhancing their metabolic stability and lipophilicity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules and probes for studying biological pathways and protein interactions.
• Catalyst Ligand Preparation: Utilized to synthesize sophisticated ligands for transition metal catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: An essential raw material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	2-Chloro-1-Iodo-3-(Trifluoromethyl)Benzene
CAS No.	1369918-95-5
Molecular Formula	C7H3ClF3I
Molecular Weight	305.45 g/mol
Synonyms	1-Chloro-2-iodo-3-(trifluoromethyl)benzene; 2-Chloro-1-iodo-3-(trifluoromethyl)benzene; 3-Trifluoromethyl-2-chloro-1-iodobenzene; 2-Chloro-α,α,α-trifluoro-o-iodotoluene; 1-Iodo-2-chloro-3-(trifluoromethyl)benzene; o-Iodo-m-chloro-α,α,α-trifluorotoluene; Benzene, 2-chloro-1-iodo-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-Iodo-3-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.