Description

1,3-Difluoro-5-isopropoxybenzene is a high-purity fluorinated aromatic ether building block, essential for advanced organic synthesis. Its molecular structure, featuring strategically placed fluorine atoms and an isopropoxy group, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates requiring fluorinated aromatic cores to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Serves as a crucial building block for novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Used in the synthesis of fluorinated components for advanced electronic displays and organic light-emitting diodes (OLEDs), contributing to improved performance and stability.
• Polymer & Specialty Chemicals: Acts as a monomer or modifier in the production of high-performance polymers, coatings, and specialty chemicals with enhanced chemical resistance and thermal properties.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create complex biaryl and heteroaryl structures.
• Chemical Research & Development: A valuable reagent for academic and industrial research exploring new fluorination methodologies and the synthesis of novel aromatic compounds.

Basic Information

Item	Details
Product Name	1,3-Difluoro-5-Isopropoxybenzene
CAS No.	1369849-69-3
Molecular Formula	C9H10F2O
Molecular Weight	172.17 g/mol
Synonyms	5-Isopropoxy-1,3-difluorobenzene; 1,3-Difluoro-5-(1-methylethoxy)benzene; Benzene, 1,3-difluoro-5-(1-methylethoxy)-; 3,5-Difluorophenyl isopropyl ether; Isopropyl 3,5-difluorophenyl ether
EINECS	Contact for details

Quality Control

Every batch of 1,3-Difluoro-5-isopropoxybenzene is manufactured and tested under strict quality management systems. We guarantee high purity and batch-to-batch consistency through comprehensive analytical protocols including GC, HPLC, and NMR. A detailed Certificate of Analysis (COA) specifying identity, purity, and impurity profiles is provided with each shipment to ensure it meets your precise research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.