Description

Benzonitrile, 4-Amino-3-(1,1-Dimethylethyl)- is a specialized aromatic nitrile derivative featuring both amino and bulky tert-butyl substituents, making it a valuable high-purity building block for advanced synthesis. This compound is critical for research and development in fine chemical and pharmaceutical manufacturing, where precise molecular architecture is required. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring specific steric and electronic properties.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the tert-butyl and amino groups contribute to biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer and Material Science: Incorporated into high-performance polymers, resins, or dyes to modify thermal stability, solubility, or optical properties.
• Organic Electronic Materials: Potential building block for charge-transport materials or emissive layers in OLEDs due to its conjugated nitrile system.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies in academic and industrial labs.

Basic Information

Product Name	Benzonitrile, 4-Amino-3-(1,1-Dimethylethyl)-
CAS No.	1369783-60-7
Molecular Formula	C11H14N2
Molecular Weight	174.25 g/mol
Synonyms	4-Amino-3-tert-butylbenzonitrile; 3-(tert-Butyl)-4-aminobenzonitrile; 4-Cyano-2-tert-butylaniline; 2-tert-Butyl-4-cyanobenzenamine; 4-Amino-3-(tert-butyl)benzonitrile; 4-Amino-3-(2-methyl-2-propanyl)benzonitrile; Benzonitrile, 4-amino-3-(1,1-dimethylethyl)-; 3-tert-Butyl-4-aminobenzonitrile
EINECS	Contact for details

Quality Control

Our Benzonitrile, 4-Amino-3-(1,1-Dimethylethyl)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and scale-up. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. While produced to meet general chemical standards, specifications can be aligned with specific project requirements, including those for GMP or ISO-guided applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.