Description

1-(2-Fluorobenzyl)-5-Methyl-1H-Pyrazole-3-Carboxylic Acid is a high-purity, fluorinated pyrazole carboxylic acid derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its precise molecular architecture, which enables the introduction of both a fluorinated benzyl group and a carboxylic acid functional group into target molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Chemical Biology Probe Development: Serves as a scaffold or linker for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Potential monomer or additive in the synthesis of specialty polymers with tailored properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects requiring this specific fluorinated pyrazole motif.

Basic Information

Product Name	1-(2-Fluorobenzyl)-5-Methyl-1H-Pyrazole-3-Carboxylic Acid
CAS No.	1368891-44-4
Molecular Formula	C12H11FN2O2
Molecular Weight	234.23 g/mol
Synonyms	5-Methyl-1-[(2-fluorophenyl)methyl]-1H-pyrazole-3-carboxylic acid; 1-[(2-Fluorophenyl)methyl]-5-methyl-1H-pyrazole-3-carboxylic acid; 1-(2-Fluorobenzyl)-5-methyl-1H-pyrazole-3-carboxylic acid; 1368891-44-4; 1H-Pyrazole-3-carboxylic acid, 1-[(2-fluorophenyl)methyl]-5-methyl-; 1-(2-Fluorobenzyl)-5-methylpyrazole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(2-Fluorobenzyl)-5-Methyl-1H-Pyrazole-3-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for advanced intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.