Description

6-Fluoroquinoline-8-Carbonitrile is a high-value, multi-functional heterocyclic building block. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals due to its unique fluorine and nitrile functional groups. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to introduce the quinoline scaffold into complex target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, antimicrobials, and anticancer agents.
• Agrochemical Synthesis: Used in the development of next-generation pesticides and herbicides, leveraging the bioactivity of the quinoline core.
• Material Science Research: Serves as a building block for creating organic semiconductors, fluorescent dyes, and advanced polymers.
• Chemical Biology Probes: Employed in the design of molecular probes and tags for studying biological processes.
• Catalyst Ligand Precursor: The nitrile and fluorine groups make it a useful starting material for synthesizing specialized ligands in catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke chemical synthesis projects.

Basic Information

Product Name	6-Fluoroquinoline-8-Carbonitrile
CAS No.	1368394-42-6
Molecular Formula	C10H5FN2
Molecular Weight	172.16 g/mol
Synonyms	8-Cyano-6-fluoroquinoline; 6-Fluoro-8-quinolinecarbonitrile; 6-Fluoroquinoline-8-carbonitrile; Quinoline, 6-fluoro-8-cyano-; 1368394-42-6; 6-Fluoro-8-cyanoquinoline; 8-Quinolinecarbonitrile, 6-fluoro-
EINECS	Contact for details

Quality Control

Our 6-Fluoroquinoline-8-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming it meets the agreed specifications for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.