Description

(2R)-1-(Diphenylphosphino)-3,3-Dimethyl-2-Butana is a chiral phosphine ligand of significant importance in asymmetric synthesis and homogeneous catalysis. Its value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, enabling the production of optically pure intermediates. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for pharmaceutical intermediate synthesis.
• Catalyst component for enantioselective C-C and C-X bond-forming cross-coupling reactions.
• Use in the synthesis of chiral active pharmaceutical ingredients (APIs) and natural products.
• Key reagent for the development of novel catalytic systems in academic and industrial R&D.
• Production of high-value specialty chemicals and flavors & fragrances requiring specific chirality.
• Asymmetric synthesis of agrochemicals and other bioactive molecules.

Basic Information

Product Name	(2R)-1-(Diphenylphosphino)-3,3-Dimethyl-2-Butana
CAS No.	1366384-12-4
Molecular Formula	C18H23P
Molecular Weight	270.35 g/mol
Synonyms	(R)-1-(Diphenylphosphino)-3,3-dimethyl-2-butanol; (R)-DTBM-SEGPHOS; (R)-DTBM-SEGPHOS Ligand; (R)-5,5'-Bis[di(3,5-di-tert-butyl-4-methoxyphenyl)phosphino]-4,4'-bi-1,3-benzodioxole; (R)-DTBM-SEGPHOS; (2R)-1-(Diphenylphosphino)-3,3-dimethylbutan-2-ol; (R)-1-(Diphenylphosphino)-3,3-dimethylbutan-2-ol; (R)-DTBM-SEGPHOS (common trade name)
EINECS	Contact for details

Quality Control

Our (2R)-1-(Diphenylphosphino)-3,3-Dimethyl-2-Butana is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive catalytic applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and chiral analysis. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.