Description

(S)-2,2'-Bis[Bis(4-Methoxy-3,5-Dimethylphenyl)Phosphino]-4,4',6,6'-Tetramethoxybiphenyl, 97+% is a high-purity, chiral bisphosphine ligand of significant importance in asymmetric catalysis. Its value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, which is critical for the efficient synthesis of single-enantiomer compounds. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control for creating advanced intermediates and active ingredients.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for pharmaceutical intermediate synthesis.
• Catalyst component for asymmetric C-C bond formation (e.g., cross-coupling, allylic substitution).
• Enantioselective synthesis of active pharmaceutical ingredients (APIs) and natural products.
• Development of novel transition metal catalysts for academic and industrial research.
• Production of chiral agrochemicals and flavor/fragrance compounds.
• Use in methodology development for stereoselective transformations in process chemistry.

Basic Information

Item	Details
Product Name	(S)-2,2'-Bis[Bis(4-Methoxy-3,5-Dimethylphenyl)Phosphino]-4,4',6,6'-Tetramethoxybiphenyl, 97+%
CAS No.	1365531-94-7
Molecular Formula	C56H68O8P2
Molecular Weight	931.08 g/mol
Synonyms	(S)-DTBM-SEGPHOS; (S)-5,5'-Bis[di(3,5-dimethyl-4-methoxyphenyl)phosphino]-4,4'-bi-1,3-benzodioxole; (S)-DTBM-Segphos; (S)-3,3',5,5'-Tetramethoxy-4,4'-biphenyldiyl)bis[bis(3,5-dimethyl-4-methoxyphenyl)phosphine]; SEGPHOS derivative; Chiral bisphosphine ligand; DTBM-SEGPHOS ligand
EINECS	Contact for details

Quality Control

Our (S)-DTBM-SEGPHOS is manufactured under strict quality protocols to ensure batch-to-batch consistency and high performance in sensitive catalytic applications. Each lot is characterized by NMR, HPLC, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry place. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain purity and catalytic activity.

Specification

Item	Specification
Appearance	White to off-white powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.