Description

(R)-2,2'-Bis[Bis(3,5-Dimethylphenyl)Phosphino]-4,4',6,6'-Tetramethoxybiphenyl, 97+% is a high-purity, chiral bisphosphine ligand of significant importance in asymmetric catalysis. Its value lies in its ability to induce high enantioselectivity in transition-metal-catalyzed reactions, enabling the synthesis of complex chiral molecules with precise stereochemical control. This product is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who are developing new synthetic routes for active pharmaceutical ingredients (APIs) and other high-value intermediates.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for the production of enantiomerically pure amino acids, amines, and alcohols.
• Catalyst component in asymmetric C-C bond-forming reactions, such as cross-coupling and allylic substitution.
• Key reagent in the research and development of novel catalytic processes for pharmaceutical synthesis.
• Use in the scale-up and manufacturing of chiral building blocks for agrochemicals and specialty chemicals.
• Critical for academic and industrial research focused on organometallic chemistry and catalyst design.

Basic Information

Product Name	(R)-2,2'-Bis[Bis(3,5-Dimethylphenyl)Phosphino]-4,4',6,6'-Tetramethoxybiphenyl, 97+%
CAS No.	1365531-89-0
Molecular Formula	C52H56O4P2
Molecular Weight	806.94 g/mol
Synonyms	(R)-DTBM-SEGPHOS; (R)-2,2'-Bis(di-3,5-xylylphosphino)-4,4',6,6'-tetramethoxy-1,1'-biphenyl; (R)-DTBM-Segphos; (R)-4,4',6,6'-Tetramethoxy-2,2'-bis[bis(3,5-dimethylphenyl)phosphino]biphenyl; (R)-DTBM-SEGPHOS Ligand; (R)-DTBM-SegPhos; (R)-DTBM-SEGPHOS, 97+%; (R)-DTBM-Segphos (Ligand)
EINECS	Contact for details

Quality Control

Our (R)-DTBM-SEGPHOS is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot is characterized by NMR, HPLC, and elemental analysis to confirm identity, purity (>97%), and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties of being easily oxidized (store under inert atmosphere) and hygroscopic (moisture-sensitive), it is recommended to store the product under an inert gas (argon or nitrogen) in a cool, dry place. For long-term stability, storage at 2-8°C is advised.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.