Description

4-Bromo-n-Methylnaphthalene-1-Carboxamide is a specialized brominated naphthalene derivative serving as a high-value synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical research and material science. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries seeking to introduce specific bromine and amide functionalities into naphthalene-based systems.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or acting as kinase inhibitors.
• Agrochemical Research: Used in the development of new generation herbicides and fungicides, where the naphthalene core provides structural rigidity and bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials or host materials in OLED devices due to the naphthalene scaffold's electronic properties.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis, particularly in cross-coupling reactions where the bromine atom serves as a handle for further functionalization.
• Material Science: Intermediate for creating advanced polymers or small-molecule additives with specific optical or thermal properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	4-Bromo-n-Methylnaphthalene-1-Carboxamide
CAS No.	1365272-43-0
Molecular Formula	C₁₂H₁₀BrNO
Molecular Weight	264.12 g/mol
Synonyms	4-Bromo-N-methyl-1-naphthamide; 1-Naphthalenecarboxamide, 4-bromo-N-methyl-; 4-Bromo-N-methylnaphthalene-1-carboxamide; N-Methyl-4-bromo-1-naphthamide; 4-Bromo-1-(N-methylcarbamoyl)naphthalene; 4-Bromo-1-naphthoic acid N-methylamide; 4-Bromo-N-methyl-1-naphthalenecarboxamide
EINECS	Contact for details

Quality Control

Our 4-Bromo-n-Methylnaphthalene-1-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.