Description

3-Fluoro-5-Methoxy-4'-Methylthiobiphenyl is a high-purity, functionalized biphenyl derivative designed for advanced chemical synthesis. This compound matters as a versatile and critical building block in the development of complex organic molecules, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific fluorine, methoxy, and thioether functionalities into their target structures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or oncology.
• Agrochemical Synthesis: Serves as a precursor in the creation of novel herbicides, fungicides, or insecticides, where the biphenyl core and substituents contribute to biological activity.
• Liquid Crystal & OLED Material Research: Used as a building block for advanced organic electronic materials, where its rigid biphenyl structure and tailored substituents can influence mesomorphic or electroluminescent properties.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis, leveraging the sulfur and oxygen donor atoms for metal coordination.
• Polymer Modification: Acts as a functional monomer or additive to impart specific characteristics, such as altered solubility or thermal stability, into polymer chains.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and functional group transformations.

Basic Information

Product Name	3-Fluoro-5-Methoxy-4'-Methylthiobiphenyl
CAS No.	1365272-00-9
Molecular Formula	C14H13FOS
Molecular Weight	248.31 g/mol
Synonyms	[4-(Methylthio)phenyl](3-fluoro-5-methoxyphenyl)methane; 1-Fluoro-3-methoxy-5-[4-(methylthio)phenyl]benzene; 3-Fluoro-5-methoxy-4'-(methylthio)-1,1'-biphenyl; 4'-Methylthio-3-fluoro-5-methoxybiphenyl; Biphenyl, 3-fluoro-5-methoxy-4'-(methylthio)-
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Methoxy-4'-Methylthiobiphenyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and GC-MS and NMR for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.