Description

2-Bromo-3,4-Dichloro-1-Fluorobenzene is a high-purity halogenated benzene derivative, a crucial building block in advanced organic synthesis. Its multi-halogenated structure makes it an exceptionally versatile intermediate for constructing complex molecules with precise electronic and steric properties. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the halogen pattern influences bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, and electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the presence of the bromine atom.
• Fluorine Chemistry Research: The fluorine substituent makes it valuable for studying structure-activity relationships and metabolic stability in bioactive compounds.
• Chemical Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2-Bromo-3,4-Dichloro-1-Fluorobenzene
CAS No.	1365271-91-5
Molecular Formula	C6H2BrCl2F
Molecular Weight	243.89 g/mol
Synonyms	1-Bromo-2,3-dichloro-4-fluorobenzene; 2,3-Dichloro-4-fluorobromobenzene; 4-Fluoro-2,3-dichlorobromobenzene; Benzene, 2-bromo-3,4-dichloro-1-fluoro-; 3,4-Dichloro-2-bromo-1-fluorobenzene; 2-Bromo-3,4-dichlorofluorobenzene
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3,4-Dichloro-1-Fluorobenzene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the exacting standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is 2-8°C for long-term stability. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.