Description

3-(2-Chloro-5-Methoxyphenyl)Benzonitrile is a high-purity, specialized organic intermediate featuring a benzonitrile core substituted with chloromethoxyphenyl groups. This compound matters for its role as a critical building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where precise molecular architecture is paramount. It is primarily needed by research and development chemists, process scale-up engineers, and manufacturers within the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with specific electronic or steric properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules requiring a substituted benzonitrile moiety.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, or insecticides where the chloromethoxyphenyl group contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for constructing complex ligands used in catalytic systems for organic transformations.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or charge-transport materials, due to its conjugated system.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tags used in biochemical and cellular research.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom chemical synthesis services catering to diverse R&D needs.

Basic Information

Product Name	3-(2-Chloro-5-Methoxyphenyl)Benzonitrile
CAS No.	1365271-89-1
Molecular Formula	C14H10ClNO
Molecular Weight	243.69 g/mol
Synonyms	2'-Chloro-5'-methoxy-[1,1'-biphenyl]-3-carbonitrile; [1,1'-Biphenyl]-3-carbonitrile, 2'-chloro-5'-methoxy-; 3-(2-Chloro-5-methoxyphenyl)benzonitrile; 2-Chloro-5-methoxy-3-cyanobiphenyl; (2-Chloro-5-methoxyphenyl)phenylacetonitrile precursor; Benzonitrile, 3-(2-chloro-5-methoxyphenyl)-; 3-Cyano-2'-chloro-5'-methoxybiphenyl
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Chloro-5-Methoxyphenyl)Benzonitrile undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing results from HPLC, NMR, and other spectroscopic methods is provided with each shipment to guarantee reliable performance in your synthetic processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.