Description

4-Bromo-n-Cyclopropylnaphthalene-1-Carboxamide is a specialized naphthalene derivative carboxamide compound, distinguished by its bromo and cyclopropyl functional groups, which are critical for modulating biological activity and physicochemical properties. This high-purity intermediate is essential for advanced research and development in pharmaceutical chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It serves the needs of medicinal chemists and process development scientists in pharmaceutical, agrochemical, and advanced material sectors seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize the potency, selectivity, and metabolic stability of lead compounds.
• Agrochemical Development: Serves as a precursor in the creation of new herbicides, fungicides, or insecticides, leveraging the bioactivity of the naphthalene core.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a scaffold for constructing more complex polycyclic systems in academic and industrial R&D.
• Material Science Precursor: Potential use in the development of organic semiconductors, liquid crystals, or photoactive materials due to its rigid, conjugated structure.

Basic Information

Product Name	4-Bromo-n-Cyclopropylnaphthalene-1-Carboxamide
CAS No.	1365271-49-3
Molecular Formula	C₁₄H₁₂BrNO
Molecular Weight	290.16 g/mol
Synonyms	4-Bromo-N-cyclopropyl-1-naphthamide; 1-Naphthalenecarboxamide, 4-bromo-N-cyclopropyl-; 4-Bromo-N-cyclopropylnaphthalene-1-carboxamide; N-Cyclopropyl-4-bromo-1-naphthamide; 4-Bromo-1-(cyclopropylcarbamoyl)naphthalene; 1365271-49-3; 4-Bromo-N-cyclopropyl-1-naphthalenecarboxamide
EINECS	Contact for details

Quality Control

Our 4-Bromo-n-Cyclopropylnaphthalene-1-Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements. Specifications are tailored to meet the stringent demands of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.