Description

(R)-Tetrahydrofuran-3-Carbonitrile is a high-value, chiral building block and intermediate in organic synthesis. This compound matters for its role in constructing complex, stereochemically defined molecules, which are critical for developing active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise three-dimensional molecular architecture.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and insecticides for enhanced efficacy and environmental safety.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialized polymers and liquid crystals with tailored optical or electronic properties.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and the exploration of new synthetic pathways.

Basic Information

Product Name	(R)-Tetrahydrofuran-3-Carbonitrile
CAS No.	1363378-15-7
Molecular Formula	C5H7NO
Molecular Weight	97.12 g/mol
Synonyms	(R)-3-Cyanotetrahydrofuran; (3R)-Oxolane-3-carbonitrile; (R)-Tetrahydro-3-furancarbonitrile; (R)-THF-3-carbonitrile; (R)-3-Tetrahydrofurylcarbonitrile; (R)-3-Furancarbonitrile, tetrahydro-; (R)-Tetrahydrofuran-3-carbonitrile; (3R)-Tetrahydrofuran-3-carbonitrile
EINECS	Contact for details

Quality Control

Our (R)-Tetrahydrofuran-3-Carbonitrile is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is characterized by comprehensive analytical techniques including chiral HPLC, GC, NMR, and mass spectrometry to confirm identity, enantiomeric excess (ee), and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.