Description

(+)-1,13-Bis(Diphenyl)Phosphino-(5Ar,8Ar,14Ar)-5A,6,7,8,8A,9-Hexahydro-5H-[1]Benzopyrano [3,2-D]Xanthene, 97% (R,R,R)-(+)-Ph-Skp is a high-purity, chiral phosphine ligand essential for asymmetric catalysis. This compound matters because it enables precise stereochemical control in the synthesis of complex pharmaceutical intermediates and fine chemicals, offering superior enantioselectivity and catalytic efficiency. It is critically needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-performance ligands for transition metal-catalyzed cross-coupling and hydrogenation reactions.

Application

• Asymmetric Hydrogenation Catalyst Ligand: A key component for the enantioselective reduction of prochiral olefins, ketones, and imines in API synthesis.
• Cross-Coupling Reactions: Used as a chiral ligand in palladium-catalyzed Suzuki-Miyaura, Heck, and Negishi couplings to construct chiral biaryl and other complex molecular architectures.
• Pharmaceutical Intermediate Synthesis: Facilitates the production of single-enantiomer drug candidates for central nervous system (CNS), cardiovascular, and oncology therapeutics.
• Agrochemical Active Ingredient Development: Enables the creation of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic and Industrial R&D: Serves as a valuable tool for methodological development in organic synthesis and catalysis research.
• Fine Chemical Manufacturing: Applied in the scalable production of specialty chemicals, flavors, and fragrances requiring high optical purity.

Basic Information

Product Name	(+)-1,13-Bis(Diphenyl)Phosphino-(5Ar,8Ar,14Ar)-5A,6,7,8,8A,9-Hexahydro-5H-[1]Benzopyrano [3,2-D]Xanthene, 97% (R,R,R)-(+)-Ph-Skp
CAS No.	1360823-43-3
Molecular Formula	C43H35O2P2
Molecular Weight	636.69 g/mol
Synonyms	(R,R,R)-(+)-Ph-Skp; (R,R,R)-(+)-1,13-Bis(diphenylphosphino)-5a,6,7,8,8a,9-hexahydro-5H-[1]benzopyrano[3,2-d]xanthene; (R,R,R)-(+)-SKP Ligand; (5aR,8aR,14aR)-5a,6,7,8,8a,9-Hexahydro-5H-[1]benzopyrano[3,2-d]xanthene-1,13-diylbis(diphenylphosphine); (+)-Ph-SKP; SKP-Ph Ligand; Chiral Diphosphine Ligand SKP
EINECS	Contact for details

Quality Control

Our (+)-1,13-Bis(Diphenyl)Phosphino-(5Ar,8Ar,14Ar)-5A,6,7,8,8A,9-Hexahydro-5H-[1]Benzopyrano [3,2-D]Xanthene, 97% (R,R,R)-(+)-Ph-Skp is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR spectroscopy, to ensure identity, purity, and enantiomeric excess meet the specified standards. Certificates of Analysis (COA) with complete chromatographic and spectroscopic data are provided to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, this material should be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.