Description

2-(Ethoxycarbonyl)-2-Fluorocyclooctanone is a specialized fluorinated organic building block featuring a cyclooctanone core functionalized with both an ethoxycarbonyl ester and a fluorine substituent. This unique structure makes it a valuable intermediate for the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research where the introduction of fluorine atoms is a key strategy to modulate bioactivity and metabolic stability. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and advanced material sectors. The compound is supplied to meet the stringent purity requirements of modern synthetic chemistry.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in the creation of fluorinated drug candidates for oncology, CNS, and metabolic diseases.
• Agrochemical Research: Used in the synthesis of advanced fluorinated pesticides and herbicides, where fluorine incorporation enhances efficacy and environmental stability.
• Material Science Precursor: Serves as a building block for fluorinated polymers or specialty chemicals with unique surface properties or thermal stability.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for method development, including fluorination studies, ring expansion reactions, and asymmetric synthesis.
• Ligand and Catalyst Development: Potential use in constructing complex, fluorinated ligands for catalysis or as a scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-(Ethoxycarbonyl)-2-Fluorocyclooctanone
CAS No.	1360544-81-5
Molecular Formula	C11H17FO3
Molecular Weight	216.25 g/mol
Synonyms	Ethyl 2-Fluoro-2-oxocyclooctanecarboxylate; 2-Fluoro-2-(ethoxycarbonyl)cyclooctanone; 2-Fluoro-2-(ethoxycarbonyl)cyclooctan-1-one; 2-Fluorocyclooctane-1-carboxylic acid, 2-oxo-, ethyl ester; 2-Fluoro-1-oxocyclooctane-1-carboxylic acid ethyl ester; 2-Fluoro-2-carbethoxycyclooctanone; 2-Fluoro-2-(carbonethoxy)cyclooctanone; 2-Fluoro-2-(ethoxycarbonyl)cyclooctanone
EINECS	Contact for details

Quality Control

Our 2-(Ethoxycarbonyl)-2-Fluorocyclooctanone is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management principles, and our analytical methods, including NMR, HPLC, and GC-MS, are validated to provide reliable data. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.