Description

Propargyl-Peg5-Tetra-Ac-β-D-Glucose CAS NO 1360446-31-6 is a high-purity, functionalized carbohydrate derivative designed for advanced bioconjugation and chemical biology research. This compound is a critical building block for the synthesis of complex glycoconjugates and probes via copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical, diagnostic, and life science sectors who require precise, site-specific modification of biomolecules for drug discovery, vaccine development, and diagnostic assay design.

Application

• Click Chemistry Reagent: Acts as a key precursor for synthesizing glycoconjugates, glycoproteins, and glycan arrays via CuAAC reactions.
• Bioconjugation & Labeling: Enables the site-specific attachment of glucose-based moieties to antibodies, peptides, proteins, and nanoparticles for targeted delivery and imaging.
• Pharmaceutical Intermediates: Serves as a sophisticated intermediate in the research and development of novel therapeutics, including antibody-drug conjugates (ADCs) and glyco-engineered biologics.
• Diagnostic Probe Synthesis: Used to create fluorescent or affinity-based probes for studying carbohydrate-protein interactions, lectin binding, and cellular uptake mechanisms.
• Material Science: Facilitates the surface functionalization of polymers and biomaterials with bioactive carbohydrate motifs to enhance biocompatibility and specific cell interactions.
• Academic & Industrial R&D: A valuable tool for fundamental research in glycoscience, chemical biology, and medicinal chemistry.

Basic Information

Product Name	Propargyl-Peg5-Tetra-Ac-β-D-Glucose
CAS No.	1360446-31-6
Molecular Formula	C31H50O17
Molecular Weight	694.72 g/mol
Synonyms	1,2,3,4-Tetra-O-acetyl-6-O-(2-(2-(2-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethoxy)ethoxy)ethoxy)ethyl)-β-D-glucopyranose; Propargyl-PEG5-Tetraacetyl-β-D-Glucose; 6-O-(Propargyl-PEG5)-1,2,3,4-tetra-O-acetyl-β-D-glucopyranose; Tetraacetylated Propargyl-PEG5-Glucose; β-D-Glucose, tetraacetate, 6-O-[2-[2-[2-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl] ether; Click Chemistry Glucose Derivative; Acetylated PEGylated Propargyl Glucose
EINECS	Contact for details

Quality Control

Our Propargyl-Peg5-Tetra-Ac-β-D-Glucose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports research and development requiring the highest standards of material integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is hygroscopic (moisture-sensitive). For long-term storage, keep under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.