Description

(5±)-17-(Cyclopropylmethyl)-4,5-Epoxy-14-Hydroxy-3-Methoxy-17-Methyl-6-Oxomorphinanium Iodide is a high-purity, specialized chemical intermediate of significant interest in advanced pharmaceutical research and development. Its complex molecular architecture makes it a valuable precursor for the synthesis of novel therapeutic agents and for use in pharmacological studies. This compound is primarily targeted toward research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex opioid receptor ligands and other specialized active pharmaceutical ingredients (APIs).
• Pharmacological Research: Used as a reference standard or experimental compound in studies investigating receptor binding affinity, metabolic pathways, and structure-activity relationships (SAR).
• Analytical Standard: Employed in method development and validation for quality control laboratories, ensuring accurate identification and quantification in complex matrices.
• Medicinal Chemistry: Provides a versatile scaffold for chemical modification and derivatization in the discovery of new drug candidates with potential analgesic or other central nervous system (CNS) activities.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant scale, optimizing yield and purity for commercial manufacturing.

Basic Information

Item	Details
Product Name	(5±)-17-(Cyclopropylmethyl)-4,5-Epoxy-14-Hydroxy-3-Methoxy-17-Methyl-6-Oxomorphinanium Iodide
CAS No.	1360001-83-7
Molecular Formula	C₂₄H₃₀INO₅
Molecular Weight	539.41 g/mol
Synonyms	17-Cyclopropylmethyl-4,5α-epoxy-14-hydroxy-3-methoxy-17-methyl-6-oxomorphinanium iodide; 6-Oxo-morphinanium derivative; Noroxymorphone cyclopropylmethyl iodide salt; 14-Hydroxy-3-methoxy-17-methyl-4,5α-epoxy-17-(cyclopropylmethyl)-6-oxomorphinanium iodide; CP-47,497 related morphinan analog
EINECS	Contact for details

Quality Control

Every batch of (5±)-17-(Cyclopropylmethyl)-4,5-Epoxy-14-Hydroxy-3-Methoxy-17-Methyl-6-Oxomorphinanium Iodide is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.