Description

(S)-2-Cyanomorpholine CAS NO 1359658-57-3 is a high-value, chiral building block and intermediate of significant importance in modern synthetic chemistry. Its core value lies in its utility for introducing the morpholine scaffold with a versatile nitrile functional group in a stereochemically defined manner. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic programs.
• Agrochemical Synthesis: Used in the research and production of advanced, stereoselective pesticides and herbicides.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Incorporated into peptide backbones to modulate biological activity and stability.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring enantiomerically pure morpholine derivatives.

Basic Information

Product Name	(S)-2-Cyanomorpholine
CAS No.	1359658-57-3
Molecular Formula	C5H8N2O
Molecular Weight	112.13 g/mol
Synonyms	(S)-Morpholine-2-carbonitrile; (2S)-Morpholine-2-carbonitrile; (S)-2-Morpholinecarbonitrile; (S)-Tetrahydro-1,4-oxazine-2-carbonitrile; (S)-2-Cyano-tetrahydro-1,4-oxazine; (S)-2-Cyano-morpholine; (S)-2-Morpholinonitrile; L-2-Cyanomorpholine
EINECS	Contact for details

Quality Control

Our (S)-2-Cyanomorpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and standard identification methods, to ensure it meets the high standards required for advanced research and GMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.