Description

2,4-Difluoro-4-Methyl-1,1-Biphenyl is a high-purity fluorinated biphenyl derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular structure, which provides a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working on new active ingredients, particularly in the life sciences sector.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system and metabolic disorders.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, where the difluoro-methyl biphenyl core contributes to bioactivity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor or dopant in the production of advanced electronic display materials due to its stable, planar aromatic structure.
• Organic Synthesis & Catalysis: Employed as a ligand or a sophisticated substrate in cross-coupling reactions and other catalytic processes to create complex molecular architectures.
• Material Science: Investigated for use in polymer modification and as a component in specialty polymers requiring specific thermal and chemical resistance properties.

Basic Information

Product Name	2,4-Difluoro-4-Methyl-1,1-Biphenyl
CAS No.	1358983-25-1
Molecular Formula	C13H10F2
Molecular Weight	204.22 g/mol
Synonyms	4-Methyl-2,4'-difluorobiphenyl; 2,4'-Difluoro-4-methylbiphenyl; 1,1'-Biphenyl, 2,4-difluoro-4'-methyl-; [1,1'-Biphenyl]-2,4-difluoro-4'-methyl; 4'-Methyl-2,4-difluorobiphenyl; 2,4-Difluoro-4'-methylbiphenyl; Biphenyl, 2,4-difluoro-4'-methyl-
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-4-Methyl-1,1-Biphenyl is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.