Description

8-(Trifluoromethyl)-3-Methoxyisoquinoline CAS NO 1357946-63-4 is a high-value, multi-functional heterocyclic building block characterized by its trifluoromethyl and methoxy substituents. This compound is essential for medicinal chemistry research and development, offering a unique scaffold for creating novel bioactive molecules. It is primarily sought after by pharmaceutical R&D teams, agrochemical innovators, and advanced material scientists for constructing complex target structures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel herbicides and pesticides, leveraging the stability imparted by the trifluoromethyl group.
• Material Science Precursor: Serves as a building block for advanced organic electronic materials and liquid crystals.
• Chemical Biology Probes: Utilized in the design of fluorescent tags and molecular probes for studying biological systems.
• Catalyst Ligand Synthesis: Acts as a precursor for creating specialized ligands used in asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	8-(Trifluoromethyl)-3-Methoxyisoquinoline
CAS No.	1357946-63-4
Molecular Formula	C11H8F3NO
Molecular Weight	227.18 g/mol
Synonyms	3-Methoxy-8-(trifluoromethyl)isoquinoline; 8-Trifluoromethyl-3-methoxyisoquinoline; 1357946-63-4; Isoquinoline, 8-(trifluoromethyl)-3-methoxy-; 3-Methoxy-8-trifluoromethylisoquinoline
EINECS	Contact for details

Quality Control

Our 8-(Trifluoromethyl)-3-Methoxyisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.