Description

Ethyl 2-Nitro-4-(Trifluoromethyl)Phenylacetate is a specialized fluorinated aromatic ester building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, combining a nitro group and a trifluoromethyl moiety on a phenylacetate ester scaffold, which is highly valuable for creating molecules with tailored electronic and steric properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing the trifluoromethyl group to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the nitro and CF3 groups contribute to biological activity.
• Liquid Crystal & OLED Material Research: Serves as a precursor for fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes.
• Functional Polymer Monomer: Employed in the synthesis of specialty polymers with specific optical or surface properties.
• Chemical Research & Development: A versatile building block for exploring novel reaction pathways and creating complex molecular structures in academic and industrial labs.

Basic Information

Product Name	Ethyl 2-Nitro-4-(Trifluoromethyl)Phenylacetate
CAS No.	1357626-53-9
Molecular Formula	C11H10F3NO4
Molecular Weight	277.20 g/mol
Synonyms	Ethyl (2-Nitro-4-(trifluoromethyl)phenyl)acetate; 2-Nitro-4-(trifluoromethyl)phenylacetic Acid Ethyl Ester; Ethyl α-(2-Nitro-4-trifluoromethylphenyl)acetate; (2-Nitro-4-(trifluoromethyl)phenyl)acetic Acid Ethyl Ester; Ethyl 2-Nitro-α-(trifluoromethyl)benzeneacetate; Benzeneacetic acid, 2-nitro-4-(trifluoromethyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Nitro-4-(Trifluoromethyl)Phenylacetate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids, organic solvents, fluorides, and strong alkalis. The container must be kept tightly closed in a dry environment.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.