Description

[1-(3-Methoxy-4-Nitro-Phenyl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific piperidine and carbamate structure. This compound is of critical importance for research and development in medicinal chemistry, serving as a key building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical companies, contract research organizations (CROs), and academic research institutions focused on developing new therapeutic agents, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of potential drug candidates targeting central nervous system (CNS) disorders, pain management, or other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Employed in the development and scale-up processes for new chemical entities (NCEs), especially those containing a functionalized piperidine moiety.
• Chemical Synthesis Reference Standard: Acts as a high-purity standard for analytical method development, quality control, and regulatory submissions.
• Process Chemistry: Utilized in route scouting and process optimization for efficient and scalable manufacturing of target molecules.

Basic Information

Product Name	[1-(3-Methoxy-4-Nitro-Phenyl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester
CAS No.	1356962-89-4
Molecular Formula	C17H25N3O5
Molecular Weight	351.40 g/mol
Synonyms	tert-Butyl N-[1-(3-methoxy-4-nitrophenyl)-4-piperidyl]carbamate; 1-(3-Methoxy-4-nitrophenyl)piperidin-4-amine, N-Boc-protected; Boc-4-amino-1-(3-methoxy-4-nitrophenyl)piperidine; N-Boc-1-(3-methoxy-4-nitrophenyl)piperidin-4-amine; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-(3-methoxy-4-nitrophenyl)piperidine; (1-(3-Methoxy-4-nitrophenyl)piperidin-4-yl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our [1-(3-Methoxy-4-Nitro-Phenyl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.