Description

Ethyl 5-(3-Fluorophenyl)Thiophene-3-Carboxylate is a high-purity fluorinated thiophene derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular architecture, which combines a thiophene core with fluorinated aromatic and ester functionalities, enabling precise modifications in target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially in medicinal chemistry programs targeting CNS disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used as a precursor in the design and synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene scaffold.
• Material Science Research: Serves as a monomer or functional component in the development of advanced organic electronic materials, such as semiconductors for OLEDs or OFETs.
• Chemical Biology Probe: Employed in the synthesis of fluorescent tags or molecular probes for studying biological processes and target engagement.
• Custom Synthesis & Scale-Up: A versatile starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	Ethyl 5-(3-Fluorophenyl)Thiophene-3-Carboxylate
CAS No.	1356151-45-5
Molecular Formula	C13H11FO2S
Molecular Weight	250.29 g/mol
Synonyms	Ethyl 5-(3-fluorophenyl)thiophene-3-carboxylate; 5-(3-Fluorophenyl)thiophene-3-carboxylic acid ethyl ester; 3-Thiophenecarboxylic acid, 5-(3-fluorophenyl)-, ethyl ester; Ethyl 5-(m-fluorophenyl)thiophene-3-carboxylate; 1356151-45-5; AKOS026711293; F2198-0073
EINECS	Contact for details

Quality Control

Our Ethyl 5-(3-Fluorophenyl)Thiophene-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.