Description

Benzene, 2-Bromo-1-Fluoro-5-Iodo-3-Methyl- CAS NO 1356114-63-0 is a highly functionalized halogenated aromatic compound, serving as a versatile and valuable advanced pharmaceutical intermediate and organic synthesis building block. Its unique substitution pattern makes it a critical precursor for constructing complex molecular architectures in medicinal chemistry and materials science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity, structurally complex intermediates for drug discovery and development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel small-molecule drugs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers with specific optoelectronic properties.
• Fluorine Chemistry: A valuable substrate for further fluorination and derivatization studies due to the presence of a reactive fluorine atom.
• Cross-Coupling Reactions: The bromo and iodo substituents make it an excellent substrate for Suzuki, Sonogashira, and other palladium-catalyzed coupling reactions.

Basic Information

Product Name	Benzene, 2-Bromo-1-Fluoro-5-Iodo-3-Methyl-
CAS No.	1356114-63-0
Molecular Formula	C7H5BrFI
Molecular Weight	314.92 g/mol
Synonyms	2-Bromo-1-fluoro-5-iodo-3-methylbenzene; 1-Bromo-2-fluoro-4-iodo-6-methylbenzene; 3-Methyl-2-bromo-1-fluoro-5-iodobenzene; 2-Bromo-1-fluoro-3-methyl-5-iodobenzene; Benzene, 1-bromo-2-fluoro-4-iodo-6-methyl-; (2-Bromo-1-fluoro-5-iodo-3-methyl)benzene
EINECS	Contact for details

Quality Control

Our Benzene, 2-Bromo-1-Fluoro-5-Iodo-3-Methyl- is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.