Description

4’-Bromo Ampicillin is a chemically modified derivative of the classic β-lactam antibiotic, ampicillin, designed for advanced pharmaceutical research and development. This specialized compound is critical for medicinal chemists exploring novel antibacterial agents and studying structure-activity relationships (SAR) to combat resistant pathogens. It serves as a key synthetic intermediate for researchers in pharmaceutical development, biotechnology, and academic institutions focused on next-generation antibiotic discovery and biochemical probing.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel β-lactam antibiotics and prodrugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new antibacterial agents with improved efficacy.
• Biochemical Research: Acts as a probe or inhibitor in enzymatic studies related to bacterial cell wall synthesis.
• Antibiotic Resistance Studies: Employed in research aimed at overcoming bacterial resistance mechanisms to traditional penicillins.
• Academic & Institutional R&D: Serves as a reference standard and synthetic target in university and institutional research laboratories.
• Custom Synthesis: A starting material for the contract manufacturing and custom synthesis of specialized active pharmaceutical ingredients (APIs).

Basic Information

Product Name	4’-Bromo Ampicillin
CAS No.	1356019-52-7
Molecular Formula	C16H18BrN3O4S
Molecular Weight	428.30 g/mol
Synonyms	4'-Bromoampicillin; (2S,5R,6R)-6-[[(2R)-2-Amino-2-(4-bromophenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 4-Bromo-D-α-aminobenzylpenicillin; Ampicillin 4'-bromo derivative; BRL 2333 (bromo analogue)
EINECS	Contact for details

Quality Control

Our 4’-Bromo Ampicillin is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research chemicals, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.