Description

(S)-((Dec-1-Yn-5-Yloxy)Methyl)Benzene is a chiral, non-racemic organic compound featuring a terminal alkyne and an ether-linked benzyl group, making it a valuable synthetic intermediate for constructing complex molecular architectures. Its primary value lies in its role as a versatile building block in asymmetric synthesis and medicinal chemistry, where its defined stereochemistry and functional handles enable precise chemical modifications. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality chiral synthons for drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs, particularly in programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of novel, stereoselective pesticides and herbicides, where the specific spatial orientation of the molecule can influence biological activity and environmental degradation profiles.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating chiral ligands, organocatalysts, and metal-organic frameworks (MOFs) used in asymmetric catalysis and enantioselective transformations.
• Material Science: Employed in the research and development of specialty polymers and liquid crystals, where its alkyne group allows for polymerization or cross-linking via click chemistry.
• Chemical Biology Probes: Utilized to synthesize molecular probes and tags for studying biological processes, leveraging the alkyne for bioorthogonal conjugation reactions like copper-catalyzed azide-alkyne cycloaddition (CuAAC).

Basic Information

Product Name	(S)-((Dec-1-Yn-5-Yloxy)Methyl)Benzene
CAS No.	1355990-11-2
Molecular Formula	C₁₇H₂₄O
Molecular Weight	244.37 g/mol
Synonyms	(S)-5-(Benzyloxy)dec-1-yne; (S)-1-(Benzyloxy)-5-decyne; (S)-((5-Decyn-1-yloxy)methyl)benzene; (S)-α-[(5-Decyn-1-yl)oxy]toluene; Benzene, [(1S)-1-(dec-1-yn-5-yloxy)methyl]-; (S)-Benzyl 5-decyn-1-yl ether; (S)-1-Benzyloxy-5-decyne
EINECS	Contact for details

Quality Control

Our (S)-((Dec-1-Yn-5-Yloxy)Methyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.