Description

Cyclohexanone, 3-(Difluoromethyl)- is a specialized fluorinated ketone building block of significant interest in advanced organic synthesis. Its core value lies in the strategic incorporation of a difluoromethyl group onto the cyclohexanone scaffold, enabling precise modulation of molecular properties such as lipophilicity, metabolic stability, and electronic characteristics. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, metabolic diseases, and oncology.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the difluoromethyl group can enhance bioactivity and environmental profile.
• Advanced Material Precursor: Serves as a monomer or modifying agent in the synthesis of specialty polymers and liquid crystals with tailored performance characteristics.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex fluorinated molecules via reactions such as nucleophilic addition, condensation, and reduction.
• Flavor & Fragrance Chemistry: Potential use in the synthesis of novel fluorinated aroma chemicals, offering unique stability and scent profiles.

Basic Information

Product Name	Cyclohexanone, 3-(Difluoromethyl)-
CAS No.	1355729-67-7
Molecular Formula	C7H10F2O
Molecular Weight	148.15 g/mol
Synonyms	3-(Difluoromethyl)cyclohexanone; 3-Difluoromethylcyclohexanone; Cyclohexanone, 3-(difluoromethyl)-; 1-(Difluoromethyl)-3-oxocyclohexane; 3-Oxocyclohexyl-1-difluoromethane
EINECS	Contact for details

Quality Control

Our Cyclohexanone, 3-(Difluoromethyl)- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR, IR, and GC-MS. We ensure compliance with relevant industry standards for fine chemical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and specification adherence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.