Description

4-(2-Fluorophenyl)-2-Methylthiazole is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the fluorine atom and thiazole ring system impart desirable biological and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate this specific scaffold into their molecular targets.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole moiety.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: A valuable substrate for investigating structure-activity relationships (SAR) and metabolic stability in medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	4-(2-Fluorophenyl)-2-Methylthiazole
CAS No.	1355248-06-4
Molecular Formula	C10H8FNS
Molecular Weight	193.24 g/mol
Synonyms	2-Methyl-4-(2-fluorophenyl)thiazole; 4-(2-Fluorophenyl)-2-methylthiazole; 2-(2-Fluorophenyl)-4-methylthiazole (isomeric); 2-Fluoro-4-(2-methylthiazol-4-yl)benzene; Thiazole, 4-(2-fluorophenyl)-2-methyl-; FPMT (abbrev.); 1355248-06-4 (CAS Registry)
EINECS	Contact for details

Quality Control

Our 4-(2-Fluorophenyl)-2-Methylthiazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.