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[3-(3-Fluoro-4-Methylphenyl)Phenyl]Acetic Acid CAS NO 1355247-84-5


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CAS No.:1355247-84-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

[3-(3-Fluoro-4-Methylphenyl)Phenyl]Acetic Acid is a high-purity, fluorinated aromatic acetic acid derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring a biphenyl core with strategically placed fluorine and methyl substituents, makes it a valuable intermediate for creating compounds with tailored electronic and steric properties. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
  • Agrochemical Synthesis: Used in the synthesis of advanced herbicides and fungicides, where the fluorine atom enhances biological activity, metabolic stability, and lipophilicity.
  • Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its ability to modify polarity and intermolecular interactions.
  • Polymer Modification: Employed to introduce functional aromatic-acetic acid groups into polymer chains, modifying thermal and mechanical properties for specialty plastics and coatings.
  • Chemical Research & Development: A versatile building block in medicinal chemistry and material science for structure-activity relationship (SAR) studies and the creation of compound libraries.

Basic Information

Product Name [3-(3-Fluoro-4-Methylphenyl)Phenyl]Acetic Acid
CAS No. 1355247-84-5
Molecular Formula C15H13FO2
Molecular Weight 244.26 g/mol
Synonyms 2-[3-(3-Fluoro-4-methylphenyl)phenyl]acetic acid; (3'-Fluoro-4'-methyl[1,1'-biphenyl]-3-yl)acetic acid; 3-(3-Fluoro-4-methylphenyl)benzenacetic acid; Biphenyl-3-acetic acid, 3'-fluoro-4'-methyl-; [1,1'-Biphenyl]-3-acetic acid, 3'-fluoro-4'-methyl-; 3-(3-Fluoro-4-methylphenyl)phenylacetic acid; α-Carboxy-3-(3-fluoro-4-methylphenyl)biphenyl
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Quality Control

Our [3-(3-Fluoro-4-Methylphenyl)Phenyl]Acetic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Conforms
Identification (IR) Conforms
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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