Description

4-[3-(Benzyloxy)Phenyl]-2-Chlorobenzonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its distinct benzonitrile core with benzyloxy and chloro substituents. This compound matters as a critical building block in modern organic synthesis, enabling the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Agrochemical Research: Serves as a versatile scaffold for developing new herbicides, fungicides, or plant growth regulators due to its substituted aromatic structure.
• Material Science: Used in the research and development of advanced organic materials, such as liquid crystals or organic semiconductors, where its molecular geometry and electronic properties are advantageous.
• Chemical Synthesis: Acts as a versatile building block for further functionalization via reactions at the nitrile group or the aromatic rings, enabling access to a wide library of derivatives.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	4-[3-(Benzyloxy)Phenyl]-2-Chlorobenzonitrile
CAS No.	1355247-40-3
Molecular Formula	C20H14ClNO
Molecular Weight	319.78 g/mol
Synonyms	2-Chloro-4'-(benzyloxy)[1,1'-biphenyl]-3-carbonitrile; 2-Chloro-4-(3-benzyloxyphenyl)benzonitrile; 4-(3-Benzyloxyphenyl)-2-chlorobenzonitrile; [1,1'-Biphenyl]-3-carbonitrile, 2-chloro-4'-(phenylmethoxy)-; 2-Chloro-4'-(phenylmethoxy)[1,1'-biphenyl]-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-[3-(Benzyloxy)Phenyl]-2-Chlorobenzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.