Description

4-(2,3-Difluorophenyl)Phenylacetic Acid is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the difluorophenyl moiety can impart desirable metabolic stability and bioavailability. Pharmaceutical research and development teams, as well as agrochemical manufacturers, need this precise chemical scaffold to create novel compounds targeting a range of therapeutic areas and crop protection solutions.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorinated structure enhances biological activity.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed in the development of electron-transport or host materials for efficient OLED devices.
• Advanced Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers with unique thermal and chemical resistance properties.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry for exploring new chemical entities and optimizing synthetic routes.

Basic Information

Product Name	4-(2,3-Difluorophenyl)Phenylacetic Acid
CAS No.	1355247-27-6
Molecular Formula	C14H10F2O2
Molecular Weight	248.23 g/mol
Synonyms	2-(4-(2,3-Difluorophenyl)phenyl)acetic acid; [1,1'-Biphenyl]-4-acetic acid, 2',3'-difluoro-; 2',3'-Difluoro[1,1'-biphenyl]-4-acetic acid; 4-(2,3-Difluorophenyl)benzeneacetic acid; (4-(2,3-Difluorophenyl)phenyl)acetic acid; 2-(4-(2,3-Difluorophenyl)phenyl)ethanoic acid; DFPPA; 2,3-DFPPAA
EINECS	Contact for details

Quality Control

Our 4-(2,3-Difluorophenyl)Phenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. Certificates of Analysis (COA) with complete batch data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.