Description

1-Fluoro-2-Isobutoxy-4-(Trifluoromethoxy)Benzene is a high-purity fluorinated aromatic ether building block of significant interest in advanced organic synthesis. Its unique structure, featuring both fluoro and trifluoromethoxy substituents, makes it a valuable intermediate for creating compounds with tailored electronic and physicochemical properties. This specialty chemical is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases, where the fluorine atoms can enhance bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the trifluoromethoxy group for improved lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the development of fluorinated components for electronic display technologies and organic light-emitting diodes (OLEDs), where its structure influences dielectric anisotropy and emission properties.
• Polymer & Material Science: Incorporated into specialty polymers and advanced materials to impart specific characteristics such as chemical resistance, thermal stability, and low surface energy.
• Chemical Research & Development: Employed as a versatile synthon in academic and industrial R&D for exploring new reactions and creating complex molecular architectures in medicinal and synthetic chemistry.

Basic Information

Item	Details
Product Name	1-Fluoro-2-Isobutoxy-4-(Trifluoromethoxy)Benzene
CAS No.	1355246-84-2
Molecular Formula	C11H12F4O2
Molecular Weight	252.21 g/mol
Synonyms	4-(Trifluoromethoxy)-1-fluoro-2-isobutoxybenzene; 2-Fluoro-5-(trifluoromethoxy)anisole, isobutyl ether; 1-Fluoro-2-(2-methylpropoxy)-4-(trifluoromethoxy)benzene; Benzene, 1-fluoro-2-isobutoxy-4-(trifluoromethoxy)-; Isobutyl 2-fluoro-5-(trifluoromethoxy)phenyl ether; FTOB building block; Fluorinated aromatic ether intermediate
EINECS	Contact for details

Quality Control

Our production of 1-Fluoro-2-Isobutoxy-4-(Trifluoromethoxy)Benzene adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity and quantify impurities. A detailed Certificate of Analysis (COA) documenting purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.