Description

2,6-Difluoro-3-(Methylthio)Phenylboronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound matters as a key Suzuki-Miyaura cross-coupling reagent, enabling the efficient construction of complex biaryl structures critical for advanced material and pharmaceutical development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs containing difluorinated biaryl motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific fluorine-substituted aromatic systems.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and semiconductors, where fluorine atoms tune electronic properties.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and asymmetric synthesis.
• Chemical Biology Probes: Utilized to synthesize labeled compounds and molecular probes for studying biological mechanisms and drug discovery.
• Custom Synthesis and Contract Manufacturing: A key reagent for custom synthesis houses and CROs/CMOs serving the global life sciences market.

Basic Information

Product Name	2,6-Difluoro-3-(Methylthio)Phenylboronic Acid Pinacol Ester
CAS No.	1355011-72-1
Molecular Formula	C₁₄H₁₉BF₂O₂S
Molecular Weight	300.17 g/mol
Synonyms	2,6-Difluoro-3-(methylthio)benzeneboronic acid pinacol ester; (2,6-Difluoro-3-(methylthio)phenyl)boronic acid pinacol ester; 2,6-Difluoro-3-methylsulfanylbenzeneboronic acid pinacol ester; Pinacol [2,6-difluoro-3-(methylthio)phenyl]boronate; Boronic acid, B-[2,6-difluoro-3-(methylthio)phenyl]-, 1,1-dimethylethyl ester; 3-Methylthio-2,6-difluorophenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-(Methylthio)Phenylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality management system supports traceability and regulatory compliance for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere to minimize exposure to moisture and oxygen, which can affect stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.