Description

tert-Butyl n-[(2-Oxocyclopentyl)Methyl]Carbamate is a specialized organic compound featuring a cyclopentanone ring and a tert-butyloxycarbonyl (Boc) protecting group. This molecular architecture makes it a critical building block in advanced organic synthesis, particularly for the construction of complex nitrogen-containing heterocycles and chiral intermediates. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams requiring high-purity, structurally defined precursors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing pyrrolidine or proline-like structures.
• Peptidomimetic Synthesis: Serves as a protected amine synthon for constructing peptide analogs and enzyme inhibitors.
• Chiral Auxiliary/Building Block: Used in asymmetric synthesis to introduce stereocenters for the production of enantiomerically pure compounds.
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Monomer: Potential monomer for specialty polymers and advanced functional materials.
• Academic & Contract Research: Employed in medicinal chemistry programs and methodological studies in university and CRO laboratories.

Basic Information

Product Name	tert-Butyl n-[(2-Oxocyclopentyl)Methyl]Carbamate
CAS No.	1354953-48-2
Molecular Formula	C11H19NO3
Molecular Weight	213.27 g/mol
Synonyms	Boc-2-oxocyclopentylmethylamine; tert-Butyl (2-oxocyclopentyl)methylcarbamate; N-Boc-2-aminomethylcyclopentanone; 1-[(tert-Butoxycarbonyl)amino]methylcyclopentan-2-one; Carbamic acid, N-[(2-oxocyclopentyl)methyl]-, 1,1-dimethylethyl ester; (2-Oxocyclopentyl)methylcarbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl n-[(2-Oxocyclopentyl)Methyl]Carbamate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality commitment supports applications in GMP-oriented development and other regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.