Description

((S)-3-Hydroxy-Pyrrolidin-1-Yl)-(3-Methyl-Thiophen-2-Yl)-Methanone is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is valued for its defined stereochemistry and functional groups, which are critical for synthesizing bioactive molecules with specific pharmacological profiles. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular targeting.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and metabolic disorder targets.
• Organic Synthesis Building Block: Used in asymmetric synthesis and medicinal chemistry to construct complex heterocyclic frameworks containing pyrrolidine and thiophene motifs.
• Ligand and Catalyst Precursor: Serves as a precursor for developing novel chiral ligands or organocatalysts used in stereoselective transformations.
• Agrochemical Research: Employed in the synthesis of novel compounds for crop protection and agrochemical discovery programs.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for fundamental chemical research and custom synthesis projects.

Basic Information

Product Name	((S)-3-Hydroxy-Pyrrolidin-1-Yl)-(3-Methyl-Thiophen-2-Yl)-Methanone
CAS No.	1354018-50-0
Molecular Formula	C10H13NO2S
Molecular Weight	211.28 g/mol
Synonyms	(S)-[(3-Hydroxypyrrolidin-1-yl)](3-methyl-2-thienyl)methanone; (S)-[3-Hydroxy-1-pyrrolidinyl](3-methyl-2-thienyl)methanone; (3-Methylthiophen-2-yl)[(3S)-3-hydroxypyrrolidin-1-yl]methanone; (S)-3-Hydroxy-1-(3-methylthiophene-2-carbonyl)pyrrolidine; 1354018-50-0; (S)-HPMM
EINECS	Contact for details

Quality Control

Our ((S)-3-Hydroxy-Pyrrolidin-1-Yl)-(3-Methyl-Thiophen-2-Yl)-Methanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.