Description

(3-Amino-Piperidin-1-Yl)-(2,3-Dihydro-Benzo[1,4]Dioxin-2-Yl)-Methanone Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, or other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new pharmacophores.
• API Development: Serves as a precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Biochemical Research: Potential use as a tool compound or ligand in biochemical assays and target validation studies.
• Custom Synthesis: Starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis for clients.

Basic Information

Item	Detail
Product Name	(3-Amino-Piperidin-1-Yl)-(2,3-Dihydro-Benzo[1,4]Dioxin-2-Yl)-Methanone Hydrochloride
CAS No.	1353988-05-2
Molecular Formula	C15H19N2O3·HCl
Molecular Weight	308.79 g/mol (Free base: 275.33 g/mol)
Synonyms	1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)-3-aminopiperidine hydrochloride; 3-Amino-1-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]piperidine hydrochloride; (3-Aminopiperidin-1-yl)(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanone hydrochloride; 1353988-05-2; UNII-8V9F1K2Q3F
EINECS	Contact for details

Quality Control

Our production of (3-Amino-Piperidin-1-Yl)-(2,3-Dihydro-Benzo[1,4]Dioxin-2-Yl)-Methanone Hydrochloride adheres to stringent internal quality standards suitable for research and development applications. Each batch is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to ensure traceability and consistency for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Assay (Titration)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.