Description

Benzo[1,3]Dioxole-5-Carboxylic Acid Methyl-Piperidin-4-Yl-Amide Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value in medicinal chemistry research and development, particularly for its role as a key building block in synthesizing novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex organic molecules requiring a piperidine and benzodioxole moiety.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in API manufacturing.
• Biochemical Tool Compound: Potential use in pharmacological studies to investigate specific receptor interactions or enzyme inhibition.

Basic Information

Product Name	Benzo[1,3]Dioxole-5-Carboxylic Acid Methyl-Piperidin-4-Yl-Amide Hydrochloride
CAS No.	1353978-56-9
Molecular Formula	C15H20N2O3·HCl
Molecular Weight	312.79 g/mol
Synonyms	1,3-Benzodioxole-5-carboxylic acid, 4-[(methylamino)carbonyl]-1-piperidinyl ester hydrochloride; Methyl-piperidin-4-yl-amide of 1,3-Benzodioxole-5-carboxylic acid hydrochloride; Piperidine-4-carboxamide, N-methyl-, 1,3-benzodioxol-5-yl ester hydrochloride; 1353978-56-9; Benzo[1,3]dioxol-5-yl 4-[(methylcarbamoyl)]piperidine-1-carboxylate hydrochloride
EINECS	Contact for details

Quality Control

Our Benzo[1,3]Dioxole-5-Carboxylic Acid Methyl-Piperidin-4-Yl-Amide Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All batches are subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.