Description

(2-Cyclopropylamino-Cyclohexyl)-Carbamic Acid tert-Butyl Ester is a specialized carbamate-protected amine building block of significant interest in advanced organic synthesis. Its core value lies in providing a versatile and protected intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where precise stereochemistry and functional group manipulation are required.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, or metabolic conditions.
• Agrochemical Research: Used in the development of new pesticides, herbicides, or fungicides where the cyclopropylamino and protected amine motifs can impart specific biological activity.
• Peptidomimetics & Bioactive Molecule Synthesis: Serves as a constrained scaffold or a chiral component for creating peptide mimics and other bioactive compounds.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function or cellular pathways.
• Process Chemistry & Scale-Up: Used in route scouting and optimization for the efficient, large-scale production of target molecules.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, including novel cyclization or coupling reactions.

Basic Information

Product Name	(2-Cyclopropylamino-Cyclohexyl)-Carbamic Acid tert-Butyl Ester
CAS No.	1353973-23-5
Molecular Formula	C₁₄H₂₆N₂O₂
Molecular Weight	254.37 g/mol
Synonyms	tert-Butyl N-(2-(cyclopropylamino)cyclohexyl)carbamate; N-Boc-2-(cyclopropylamino)cyclohexylamine; 2-(Cyclopropylamino)cyclohexanamine, N-Boc derivative; Boc-2-(cyclopropylamino)cyclohexylamine; (2-(Cyclopropylamino)cyclohexyl)carbamic acid tert-butyl ester; 1-Boc-2-(cyclopropylamino)cyclohexylamine; N-(tert-Butoxycarbonyl)-2-(cyclopropylamino)cyclohexylamine
EINECS	Contact for details

Quality Control

Our (2-Cyclopropylamino-Cyclohexyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (NMR, IR, MS) to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming specifications for assay, enantiomeric excess (if applicable), and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.