Description

1-(3-Iodo-Piperidin-1-Yl)-Ethanone is a specialized piperidine derivative featuring an iodo-substituent and an acetyl group, serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel pharmaceuticals and bioactive molecules, enabling key structural modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and life science industries for constructing complex nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, enzyme inhibitors, and receptor modulators.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the piperidine scaffold for biological activity.
• Chemical Biology Probe Development: Serves as a scaffold for creating molecular probes to study protein-ligand interactions and cellular pathways.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies through further functionalization of the iodine atom via cross-coupling reactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring specific, high-purity heterocyclic intermediates.

Basic Information

Product Name	1-(3-Iodo-Piperidin-1-Yl)-Ethanone
CAS No.	1353971-15-9
Molecular Formula	C7H12INO
Molecular Weight	253.08 g/mol
Synonyms	1-(3-Iodopiperidin-1-yl)ethanone; 1-Acetyl-3-iodopiperidine; 3-Iodo-1-acetylpiperidine; Ethanone, 1-(3-iodo-1-piperidinyl)-; N-Acetyl-3-iodopiperidine; 1-(3-Iodo-1-piperidinyl)ethanone; 3-Iodo-N-acetylpiperidine; 1353971-15-9
EINECS	Contact for details

Quality Control

Our 1-(3-Iodo-Piperidin-1-Yl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and IR are available upon request. We adhere to cGMP standards for pharmaceutical-grade intermediates to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.