Description

3-[(3-Methyl-Thiophene-2-Carbonyl)-Amino]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for constructing molecules with specific biological activity. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Peptidomimetic Synthesis: Serves as a constrained scaffold for creating peptide-like molecules with improved metabolic stability.
• Custom Synthesis: Employed in the contract manufacturing of specialized APIs for clinical trials and commercial production.
• Chemical Biology Probes: Utilized in the development of tool compounds for target validation and pathway analysis.

Basic Information

Product Name	3-[(3-Methyl-Thiophene-2-Carbonyl)-Amino]-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1353965-53-3
Molecular Formula	C17H26N2O3S
Molecular Weight	338.47 g/mol
Synonyms	1-Boc-3-[(3-methyl-2-thiophenecarbonyl)amino]piperidine; tert-Butyl 3-[(3-methylthiophene-2-carbonyl)amino]piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-[(3-methyl-2-thienylcarbonyl)amino]piperidine; 3-[(3-Methyl-2-thienoyl)amino]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 3-[(3-Methylthiophene-2-carbonyl)amino]piperidine-1-carboxylic acid tert-butyl ester; N-(1-Boc-3-piperidinyl)-3-methyl-2-thiophenecarboxamide; 3-[(3-Methyl-2-thiophenecarbonyl)amino]-1-piperidinecarboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 3-[(3-Methyl-Thiophene-2-Carbonyl)-Amino]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We adhere to cGMP guidelines for the production of pharmaceutical intermediates to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.