Description

4-[(Carboxymethyl-Methyl-Amino)-Methyl]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a piperidine scaffold with a protected carboxylic acid and a versatile amino acid side chain. This compound is critical for medicinal chemistry research and development, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for creating novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to introduce specific functional groups and modulate physicochemical properties.
• Peptidomimetic Synthesis: Serves as a constrained amino acid analog for constructing peptide-like structures with enhanced stability and bioavailability.
• Ligand Development: Employed in the creation of novel ligands for receptors and enzymes, useful in drug discovery and biochemical tool development.
• Chemical Biology Probes: Facilitates the development of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	4-[(Carboxymethyl-Methyl-Amino)-Methyl]-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1353960-10-7
Molecular Formula	C15H28N2O4
Molecular Weight	300.40 g/mol
Synonyms	1-Boc-4-[(N-methylcarboxymethylamino)methyl]piperidine; 4-[(Carboxymethyl-methylamino)methyl]piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-[(carboxymethyl)(methyl)amino]methyl]piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-[(N-methylglycyl)aminomethyl]piperidine; 4-[(N-Methylaminoacetate)methyl]-1-Boc-piperidine; 4-[(Methyl(carboxymethyl)amino)methyl]piperidine-1-carboxylic acid 1,1-dimethylethyl ester; 1353960-10-7; Boc-4-((N-methylglycyl)aminomethyl)piperidine
EINECS	Contact for details

Quality Control

Our 4-[(Carboxymethyl-Methyl-Amino)-Methyl]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.