Description

Albendazole-D3 is a deuterated analog of the broad-spectrum anthelmintic drug Albendazole, specifically labeled with three deuterium atoms. This stable isotope-labeled compound is an essential reference standard and internal standard for precise quantitative analysis in complex biological matrices. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities engaged in drug metabolism, pharmacokinetic (DMPK) studies, and bioanalytical method development.

Application

• Primary use as an internal standard for the accurate quantification of Albendazole and its metabolites in bioanalytical assays using LC-MS/MS and GC-MS.
• Critical component in drug metabolism and pharmacokinetic (DMPK) studies to understand absorption, distribution, metabolism, and excretion (ADME) profiles.
• Reference material for method development and validation in pharmaceutical quality control and forensic toxicology laboratories.
• Used in clinical research for monitoring drug levels in plasma, serum, and other biological fluids during therapeutic drug monitoring (TDM).
• Essential for veterinary pharmaceutical research analyzing anthelmintic drug residues in animal tissues and products.
• Tool in environmental science for tracing pharmaceutical pollutants and studying their degradation pathways.

Basic Information

Product Name	Albendazole-D3
CAS No.	1353867-92-1
Molecular Formula	C12H12D3N3O2S
Molecular Weight	268.33 g/mol (approx.)
Synonyms	Albendazole-methyl-d3; Albendazole (methyl-d3); 5-(Propylthio)-1H-benzimidazol-2-yl-d3 carbamic acid methyl ester; Methyl 5-(propylthio)-2-benzimidazolecarbamate-d3; NSC 758724-d3; SKF 62979-d3; [Methyl-d3]albendazole; Albendazole D3; Albendazole-d3 internal standard
EINECS	Contact for details

Quality Control

Our Albendazole-D3 is manufactured under strict quality systems to ensure high chemical and isotopic purity suitable for sensitive analytical applications. Each batch is characterized by advanced spectroscopic techniques (NMR, MS) and undergoes rigorous purity analysis by HPLC. A comprehensive Certificate of Analysis (COA) is provided, detailing batch-specific data including chemical purity, isotopic enrichment (D%), and residual solvent content, ensuring traceability and compliance with research standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C under inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D%)	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.