Description

4-Bromo-2-Cyclopropylbenzonitrile is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its unique structure, featuring a bromine substituent, a nitrile group, and a cyclopropyl ring, makes it a critical precursor for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing active pharmaceutical ingredients (APIs) and novel functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and pesticides, leveraging the bioactivity of the cyclopropyl and benzonitrile motifs.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in cross-coupling reactions and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers due to its rigid, aromatic core and functional handles for further modification.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	4-Bromo-2-Cyclopropylbenzonitrile
CAS No.	1353854-27-9
Molecular Formula	C10H8BrN
Molecular Weight	222.08 g/mol
Synonyms	2-Cyclopropyl-4-bromobenzonitrile; 4-Bromo-2-cyclopropylbenzonitrile; Benzonitrile, 4-bromo-2-cyclopropyl-; 4-Bromo-2-cyclopropyl-benzonitrile
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Cyclopropylbenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting cGMP, ISO, and other relevant regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.